CustomizeGoogle and Kiva.org
You can go to Kiva's website and lend to someone in the developing world who needs a loan for their business - like raising goats, selling vegetables at market or making bricks. Each loan has a picture of the entrepreneur, a description of their business and how they plan to use the loan so you know exactly how your money is being spent - and you get updates letting you know how the business is going. Kiva's loans are managed by microfinance institutions on the ground who have a lot of experience doing this, so you can trust that your money is being handled responsibly.
More info:
http://www.kiva.org
http://video.on.nytimes.com/?fr_story=FEEDROOM186917
http://www.kiva.org/lender/customizegoogle